Kimiyya Mai Girma: Fannin Yakarin Ciwon Daji Na Tsarin Kwayoyin Halitta A Jiki Yana Nuna Fasa-Fasawa A Binciken Mice
Stanford, California – Yuli 16, 2025 – Masu bincike a Jami’ar Stanford sun yi wani muhimmin ci gaba a fannin yakar cutar kansa, inda suka nuna cewa kwayoyin halittar CAR-T da aka kirkira a cikin jikin dabbobi (mice) sun nuna sakamako mai kyau tare da kasancewa cikin aminci. Wannan sabuwar hanyar, wanda aka bayyana a wani bincike da aka buga a ranar Litinin, na iya kawo sauyi ga yadda ake bi da cutar kansa a nan gaba, ta hanyar rage matsalolin da ke tattare da hanyoyin samar da CAR-T da ake amfani da su a yanzu.
Kwayoyin CAR-T, wanda ke nufin “Chimeric Antigen Receptor T-cells,” wani nau’i ne na kwayoyin rigakafin jiki da aka gyara a dakin gwaje-gwaje don gane da kuma kai hari kan kwayoyin cutar kansa. A halin yanzu, hanyar samar da wadannan kwayoyin na bukatar daukar kwayoyin rigakafin jikin marasa lafiya daga jikinsu, gyara su a dakin gwaje-gwaje, sannan a mayar da su jiki. Duk da nasarorin da aka samu, wannan tsari na iya daukar lokaci mai tsawo, tsada, kuma yana iya fuskantar matsaloli kamar yiwuwar kamuwa da cuta ko kuma rashin samun isassun kwayoyin rigakafin da za a gyara.
Binciken da aka yi a Stanford ya gabatar da wata sabuwar dabarar da ake kira “in situ CAR-T generation,” wanda ke nufin kirkirar kwayoyin CAR-T kai tsaye a cikin jikin dabbobi. Ta hanyar amfani da wata hanyar samar da kwayoyin rigakafin jiki na musamman, masu binciken sun iya shirya kwayoyin jiki su fara samar da kwayoyin CAR-T a lokacin da suke cikin jikin dabbobi. Sakamakon haka, wadannan kwayoyin CAR-T da aka kirkira a cikin jiki sun iya gane da kuma kashe kwayoyin cutar kansa da ke tasowa a cikin dabbobin.
Mahimmancin wannan binciken ya ta’allaka ne a kan aminci da kuma ingancin da aka gani a cikin dabbobin. Masu binciken sun lura cewa hanyar kirkirar kwayoyin CAR-T a cikin jiki ta kasance cikin aminci, ba tare da wani illa mai tsanani ba. Bugu da kari, kwayoyin CAR-T da aka kirkira a cikin jikin sun nuna ikon murkushe cutar kansa, wanda ke nuni da yiwuwar wannan hanyar a matsayin wata muhimmiyar madadin ga hanyoyin samar da CAR-T na gargajiya.
Idan wannan hanyar ta ci gaba da samun nasara a gwaje-gwajen da za a yi a nan gaba a kan mutane, za ta iya rage nauyin da ke kan marasa lafiya da kuma tsarin kiwon lafiya. Za a iya samun kwayoyin CAR-T da sauri, tare da rage kashe-kashe, kuma mai yiwuwa a iya samun damar samun wannan maganin ga wasu marasa lafiya da ba su da damar samun shi a halin yanzu.
Wannan ci gaba yana nuna alkawarin da ke tattare da kirkire-kirkiren kimiyya a fannin yakar cutar kansa, kuma yana ba da bege ga marasa lafiya da ke fama da wannan cuta mai hatsari. Masu binciken na Jami’ar Stanford suna ci gaba da bincike don fahimtar cikakken tasirin wannan sabuwar hanyar da kuma yadda za a iya amfani da ita wajen magance cutar kansa a kan mutane.
Cancer-fighting CAR-T cells generated in the body prove safe and effective in mice
AI ta bayar da labari.
An yi amfani da tambayar mai zuwa don samar da amsa daga Google Gemini:
‘Cancer-fighting CAR-T cells generated in the body prove safe and effective in mice’ an rubuta ta Stanford University a 2025-07-16 00:00. Da fatan za a rubuta cikakken bayani mai laushi. Da fatan za a amsa a cikin Hausa tare da labarin kawai.